What is Eklira Genuair?
Eklira Genuair is a long-acting anticholinergic agent (LAMA) with the active substance alidinium bromide. It is used for bronchial-enhancing continuous therapy in chronic obstructive lung disease (COPD).
Unlike Spiriva (Tiotropium), Eklira 2x is inhaled daily. The Genuair inhaler is particularly user-friendly with a color change control system that indicates whether the inhalation has been performed correctly.
Eklira is made by AstraZeneca.
Active Ingredients & Mechanism of Action
Active ingredient: Aclidiniumbromid
Aclidinium blocks muscular receptors:
Active mechanism:
- inhibits muscarin receptors M3 in the bronchial muscle
- Blocks the action of acetylcholine
- Bronchial muscle relaxes
- airways remain open
Special features:
- Fast hydrolysis in plasma (low systemic action)
- As a result, fewer anticholinergic side effects
- duration of action approx. 12 hours (2x daily administration)
Time:
- Effective entry: 15-30 minutes
- duration of action: 12 hours
Who is it suitable for?
Eklira Genuair is suitable for:
- COPD continuous therapy in adults
- as monotherapy or in combination with other bronchodilatators
Advantages:
- Fast hydrolysis = less systemic side effects
- Genuair with feedback system
- 2x daily administration for uniform 24-hour protection
Not suitable:
- For asthma (not approved)
- As an emergency medication
- For children and young people
Available Dosages
Eklira Genuair:
- 322 μg of aclidinium per single dose
- 1 inhalation 2x daily (morning and evening)
** Always inhale at the same time of day.
How to Take
Genuair inhaler: 1. Remove protective cap Two. Keep device horizontal 3. Press and release green button (control window becomes green) 4. Breathe deep (not in the inhaler) Five. Close the mouthpiece 6. Strong and deep breathing 7. Keep breath 8. Control window changes to red = correct inhalation 9. cap close
Color control:
- Green = ready to inhale
- Red = Inhalation successful
Contraindications
Do not apply at:
- hypersensitivity to aclidinium
Preview at:
- Engangle glaucoma
- Prostate hyperplasia with urine retention
- Heavy kidney failure
pregnant: Limited data. Only with clear indication.
Style time: Not recommended.
Possible Side Effects
Acid (1-10%):
- Headaches
- Nasopharyngitis
- Coughs
- diarrhea
Occasionally:
- Mouth dryness
- Sinusitis
- Hidden vision
- Tachycardia
- Harnverhalt
Selten:
- Paradox bronchospasmus
- Engangle glaucoma
** Due to the rapid hydrolysis in the blood systemic anticholinergic side effects are less common than in tiotropium.
Interactions
Preview at:
- Other anticholinergics (additive action)
- Medications with anticholine properties
No relevant interaction with:
- Beta-2-agonists (sense combination)
- Inhalative corticoids
Frequently Asked Questions
Similar Medications
Is Eklira Genuair right for you?
A licensed doctor will review your information and issue a prescription if suitable. Discreet and secure.
Important Notice
This information does not replace medical advice. If you have questions about your health or the suitability of this medication, please consult a doctor. Read the package leaflet before use.