What is fluicason?
Fluticason generics contain the active ingredient Fluticasonpropionate and are active ingredient-like with the original preparation Flutide. They are used as basic therapy for long-term treatment of asthma bronchiale.
Fluticason is one of the most potent inhalative corticoids and is used in lower doses than Budesonid or Beclometason. It has low oral bioavailability and therefore little systemic side effects.
Available, for example, as Fluticason Cipla® or as combination preparation Salmeterol/Fluticasonpropionate. When combined with Salmeterol, it acts like seretides.
Active Ingredients & Mechanism of Action
Active ingredient: Fluticasonpropionat
Fluticasonpropionate has a strong anti-inflammatory effect:
Active mechanism: 1. Binding with high affinity of glucocorticoid receptors Two. The complex migrates into the cell nucleus 3. Activates anti-inflammatory genes 4. Inhibits proinflammatory cytokines
Pharmacological benefits:
- Highest receptor affinity among ICS
- Oral bioavailability < 1% (almost only local effect)
- High lipophilia – good retention in lung tissue
- Strong and persistent anti-inflammatory effect
equivalence doses: 100 μg Fluticason ≅200 μg Budesonid ≅200 μg Beclometason
Who is it suitable for?
Fluticason generics are suitable for:
- Asthma bronchiale all heavy grades
- Adults and children (depending on formulation)
- As a basic therapy (controller)
Advantages of generic medicine:
- Same active ingredient as tidal
- Cost-effective
- Proven effectiveness
Not suitable:
- For the acute treatment of breathlessness
- In patients under Ritonavir therapy (CYP3A4 interaction!)
Available Dosages
Fluticason Cipla / Generika:
- 50 μg, 125 μg, 250 μg per stroke
Salmeterol/Fluticasonpropionate (combination):
- 50/100 μg, 50/250 μg, 50/500 μg per dose
Dosing with asthma (adults):
- Easy: 100-250 μg 2x daily
- Medium: 250-500 μg 2x daily
- Heavy: 500-1000 μg 2x daily
Equivalence doses note: Fluticason is twice as potent as Budesonid!
How to Take
Dosieraerosol: 1. Remove protective cap, shake Two. Deep exhalation 3. Close the mouthpiece 4. slowly inhale, triggering spray Five. Keep breath 10 seconds 6. Rinse and sprinkle
Powder inhaler (if available):
- Breath controlled – vigorous breathing
- rinse mouth after inhalation
Important:
- Regular use, 2x daily
- rinse mouth after each inhalation
- Do not drop abruptly
Contraindications
Do not apply at:
- Hypersensitivity to Fluticason
- Simultaneous therapy with Ritonavir or Cobicistat (Cushing Risk!)
Preview at:
- Active lung tuberculosis
- Mushroom infections of the respiratory tract
- Heavy liver failure
pregnant: Can be used with asthma.
Style time: Application possible. Low systemic exposure.
Possible Side Effects
Acid (1-10%):
- Mundsoor
- Heiserkeit
- Rache irritation
Occasionally:
- Headaches
- Taste disorders
Selten (at high doses):
- Adrenal suppression
- osteoporosis
- Cataract, glaucoma
- slowing growth in children
Important: Special caution at CYP3A4 inhibitors – systemic floodicason mirrors can dramatically increase!
Interactions
Critical interaction:
- Ritonavir, Cobicistat – CONTRAINDICES! Highly elevated systemic Fluticason mirror, Cushing syndrome possible
- Ketoconazole, Itraconazole – raised mirror
For HIV therapy: Avoid Floicason! Alternative: Beclometason.
No relevant interaction with:
- Bronchodilatators
- Antihistamines
Frequently Asked Questions
Similar Medications
Is fluicason right for you?
A licensed doctor will review your information and issue a prescription if suitable. Discreet and secure.
Important Notice
This information does not replace medical advice. If you have questions about your health or the suitability of this medication, please consult a doctor. Read the package leaflet before use.