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What is Hezku?
Hezkue is a oral spray with the active ingredient Sildenafil for the treatment of erectile dysfunction. The spray is sprayed into the oral cavity where the active substance is absorbed via the oral mucosa.
The advantage over tablets: The absorption via the oral mucosa partially bypasses the first-pass effect in the liver and can lead to a faster action. In addition, the application is discrete and requires no water.
Sildenafil is the proven active ingredient from Viagra and belongs to the group of PDE-5 inhibitors that support erection when sexually excited.
Active Ingredients & Mechanism of Action
Active ingredient: Sildenafil 13,5 mg pro Sprühstoß
Sildenafil as PDE-5 inhibitors:
Active mechanism: 1. In sexual excitation, nitrogen monoxide (NO) is released Two. NO activates guanylate cyclase → cGMP rises 3. cGMP relaxes the swelling muscle 4. Sildenafil inhibits PDE-5 (develops cGMP) Five. cGMP remains effective for longer → stronger erection
Speciality of spray:
- Recording via oral mucosa (sublingual/buccal)
- Partly bypassing the First Pass effect
- Possibly faster action than tablets
Time:
- Effective entry: 15-30 minutes
- duration of action: 4-6 hours
- Sexual stimulation continues to be necessary!
Who is it suitable for?
Hezkue is suitable for:
- Erectile dysfunction in adult men
- Men who swallow unfamiliar tablets
- Men wishing to have a faster impact
- Discrete application
Advantages:
- No water needed to swallow
- Discrete application
- Quick intake via oral mucosa
- Proven active ingredient Sildenafil
Not suitable:
- At the same time, Nitrat take!
- Heavy cardiovascular diseases
- Recent stroke or heart attack
Available Dosages
Hezkue oral spray:
- 13.5 mg Sildenafil per spray
Recommended dose:
- Start dose: 3-4 spray strokes (approx. 40-54 mg)
- Maximum single dose: 8 spray strokes (approx. 108 mg)
- 15-60 minutes before intercourse
**
- Maximum 1 application per 24 hours
- Customize dose individually
How to Take
Application: 1. Remove protective cap Two. Spray into the oral cavity (side of the cheek) 3. Do not swallow – let the mouth work 4. 15-60 minutes before intercourse
Important notes:
- Sexual stimulation is still necessary
- Heavy meals can delay the effect
- Alcohol in dimensions
- Not more than 1x per day
Contraindications
** CONTRAINDICES
- Nitrate intake (nitroglycerol, isosorbide) – life-threatening blood pressure drop!
- Heavy heart failure
- Recent heart attack or stroke (< 6 months)
- Heavy liver failure
- Hypotension (blood pressure < 90/50 mmHg)
- Retinitis pigmentosa
Preview at:
- Penis Deformities (Peyronie)
- leukemia, sickle cell anemia (priapism risk)
- bleeding tendency
Note: For erection > 4 hours (priapism) immediately not physician!
Possible Side Effects
Acid (1-10%):
- Headaches
- Face redness (Flush)
- Blocked nose
- Indigestion
- visual disorders (blue eggs)
- Squeeze
Occasionally:
- Heart palp
- muscle pain
- nausea
- Skin rash
Selten, but seriously:
- Priapism (> 4 hours)
- Sudden hearing loss
- Sudden visual loss (NAION)
** Most side effects are mild and temporary.
Interactions
CONTRAINDICES:
- Nitrate and NO donors – LIVING BEDROHLICH!
- Riociguat
Preview at:
- Alpha blockers – blood pressure drop
- CYP3A4 inhibitors (Ketoconazole, Ritonavir) – increased Sildenafil levels
- Other PDE-5 inhibitors – do not combine
** If necessary, take alpha blockers and sydenafil in time offset.
Frequently Asked Questions
Similar Medications
Is Hezku right for you?
A licensed doctor will review your information and issue a prescription if suitable. Discreet and secure.
Important Notice
This information does not replace medical advice. If you have questions about your health or the suitability of this medication, please consult a doctor. Read the package leaflet before use.