What is famenita?
Famenita contains micronized progesterone – a bioidentical hormone that is chemically identical to the body's own progesterone. It is used in hormone replacement therapy as stag protection for the cervical mucosa.
Women with intact uterus that receive estrogen additionally need a gestagen to protect the cervical mucosa from excessive growth. Micronized progesterone is considered the most natural form of gestagen protection.
Famenita can be administered orally or vaginally and is available in dosages of 100 mg and 200 mg.
Active Ingredients & Mechanism of Action
Active ingredient: Progesteron (mikronisiert) 100 mg / 200 mg
Micronized progesterone acts like the body's hormone:
Active mechanism:
- Ties to progesterone receptors in the cervical mucosa
- Converts the mucous membrane from the structure to the secretion phase
- Prevents excessive growth (hyperplasia)
- Protects against endometrium carcinoma under estrogen therapy
micronization:
- Progesterone is comminuted in tiny particles
- Better absorption in the intestine
- Higher bioavailability as non-micronized progesterone
Additional effects:
- Slightly sleep-promoting (especially when taken in the evening)
- Anxiolytically (anxiolytically) by metabolites Allopregnanolone
- More favourable risk profile than synthetic gestagenne
Who is it suitable for?
Famenita is suitable for:
- Stage protection at HRT (women with uterus)
- Sequencing therapy (12-14 days per month)
- Continuous therapy (daily)
- Women who prefer bioidentical hormones
Advantages:
- Bioidentical with body-specific progesterone
- Sleep-promoting when taken in the evening
- More favourable breast cancer risk profile than synthetic gestagens
Not suitable:
- As a contraceptive
- For peanut allergy (containing peanut oil)
Available Dosages
Famenita capsules:
- 100 mg and 200 mg
Sequenceal therapy:
- 200 mg in the evening, on 12-14 days per month
Continuous therapy:
- 100 mg daily in the evening
Vaginal application:
- 200 mg vaginal, on 12-14 days per month
- Less drowsiness than oral intake
Intake time: In the evening before sleeping (sleep-promoting).
How to Take
Oral intake:
- Evening before bedtime with some water
- sober or with light meal
- Uses the sleeping effect
Vaginal application:
- Insert capsule deep into the vagina
- Evening before bedtime
- Less systemic side effects
Important:
- Don't take in the morning (swellness, dizziness!)
- For peanut or soy allergy: do not apply
- Regular gynecological controls
Contraindications
Do not apply at:
- Breast cancer (known or suspected)
- Unexplained vaginal bleeding
- Heavy liver disease
- Active thrombosis
- Peanut or soya allergy (contains peanut oil/soya lecithin)
Preview at:
- Depression
- Epilepsy
- Migraine
- Diabetes
- Asthma
pregnant: Not indicated in the HRT.
Possible Side Effects
**
- Sleepiness (with oral intake – desired in the evening)
- Squeeze
- Headaches
- Breast tensions
Occasionally:
- Blowing
- Mood changes
- Intermediate bleeding
- nausea
Selten:
- Depression
- Acne
- Urtikaria
** The drowsiness is significantly lower in vaginal use.
Interactions
Reactions:
- CYP3A4 inductors (Carbamazepine, Rifampicin) – reduced action
- Ketoconazole – increased progesterone levels
- Alcohol - increased sedation
** Less interactions than with synthetic gestagens.
Frequently Asked Questions
Similar Medications
Is famenita right for you?
A licensed doctor will review your information and issue a prescription if suitable. Discreet and secure.
Important Notice
This information does not replace medical advice. If you have questions about your health or the suitability of this medication, please consult a doctor. Read the package leaflet before use.