What is gyncadine?
Gynokadin is an estradiol gel for transdermal (via the skin) hormone replacement therapy (HRT). It is applied daily to the skin and supplies the body's estrogen estradiol.
The transdermal application has advantages over tablets: The estrogen goes directly into the blood without first passing the liver. This reduces the risk of thrombosis and side effects.
In women with uterus, a gestagen must also be taken (e.g. as a tablet or combined preparation).
Active Ingredients & Mechanism of Action
Active ingredient: Estradiol
Estradiol:
- Is the main estrogen of the woman
- Is absorbed by the skin
- Replaces the body's own estrogen sinking in the changing years
Effects:
- Relieving heat flashes and welding outbreaks
- Improvement of sleep disorders
- Protection against vaginal drought
- Protection against osteoporosis
- Improving quality of life
Who is it suitable for?
Gynokadin is suitable for:
- Women with alternating-year complaints
- Women with surgically conditioned alternating years
- Women with estrogen deficiency
Advanced by:
- Increased risk of thrombosis (transdermal better than oral HRT)
- Liver disease
- Bubble disease
- Migraine
Available Dosages
Gynokadin dosing gel:
- 0.6 mg of estradiol per stroke
- dosing dispenser with precise dispensing
Dosing:
- usual: 1-2 strokes daily
- Customizable
- Use the lowest effective dose
How to Take
Application:
- Apply to the skin once a day
- Suitable places: upper arms, shoulders, thighs, abdomen
- Do not apply to the chest
- Let in, do not rub
- Allow to dry for 5 minutes before tightening
- Wash hands after application
Important:
- Always apply at the same time
- Changing skin site daily
Contraindications
- Breast cancer (current or prehistory)
- Estrogen-dependent tumors
- Inexplicable vaginal bleeding
- Acute or earlier thrombosis
- Heavy liver disease
- Porphyry
- Pregnancy/style
Possible Side Effects
**
- Breast tensions
- Headaches
- nausea
- bleeding/pain bleeding
Occasionally:
- Weight gain
- mood swings
- Skin irritation at application site
Selten:
- thromboses (lower than oral HRT)
Interactions
- Enzyme inductors (Johanniskraut, Antiepileptics) can reduce action
- thyroid hormones: dose adjustment possibly necessary
Frequently Asked Questions
Similar Medications
Is gyncadine right for you?
A licensed doctor will review your information and issue a prescription if suitable. Discreet and secure.
Important Notice
This information does not replace medical advice. If you have questions about your health or the suitability of this medication, please consult a doctor. Read the package leaflet before use.





