What is ovestine?
Ovestin contains estriol, a weak natural estrogen that is applied locally in the vaginal range. It is used to treat complaints due to lack of estrogen in the intimate area – often after the change years.
Ovestin is available as vaginal cream and as vaginal cups (Ovula). Since estriol only acts locally and hardly reaches the bloodstream, it has significantly fewer systemic side effects than oral hormone replacement therapies.
Active Ingredients & Mechanism of Action
Active ingredient: Estriol
Estriol:
- Is one of the three natural estrogens (besides estradiol and estrone)
- Works weaker and shorter than estradiol
- Is absorbed by vaginal tissue and acts locally
Effects:
- Improving mucosa circulation
- Normalization of vaginal pH
- Construction of vaginal mucosa
- Improving elasticity
Who is it suitable for?
Ovestin is suitable for:
- Scheidentrockenheit after the change years
- Pain in sexual intercourse due to estrogen deficiency
- Recurring urinary path infections due to atrophic mucosa
- Itching and burning intimacy
- Before/after gynecological interventions
Also often possible for women with contraindications against systemic HRT.
Available Dosages
Ovestin cream:
- 1 mg estriol per gram of cream
- Can be metered with applicator
Ovestin Ovula:
- 0.5 mg of estriol per cup
Dosing:
- Initial: 1x daily for 2-3 weeks
- Maintenance: 2x weekly
How to Take
Creme:
- Insert the applicator into the vagina
- Evening before bedtime
- Clean applicator after use
Chapters:
- introduce deep into the vagina
- Apply night
- Slip insert recommended
Contraindications
Absolute contraindications:
- Known or suspected breast cancer
- Estrogen-dependent tumors
- Inexplicable vaginal bleeding
- Acute thromboemboly
- Heavy liver disease
Relative contraindications:
- Previous thrombosis
- Endometriosis
- Myome
Possible Side Effects
Local (often at the beginning):
- Light burning when used
- Increased outflow
- Itching
Selten:
- Breast tensions
- nausea
- Headaches
Systemic side effects are very rare in local application.
Frequently Asked Questions
Similar Medications
Is ovestine right for you?
A licensed doctor will review your information and issue a prescription if suitable. Discreet and secure.
Important Notice
This information does not replace medical advice. If you have questions about your health or the suitability of this medication, please consult a doctor. Read the package leaflet before use.