What is Verification?
Veregen® is a vegetable ointment with spinecatechins (10%), a standardized extract of green tea leaves (Camellia sinensis). It is used for the treatment of external genital and perianal warts in adults.
The ointment contains a mixture of catechins, epigallocatechingallate (EGCG) being the main active ingredient. Veregen® offers a herbal alternative to imiquimod and Podophyllotoxin and has shown comparable efficacy in clinical studies with a low relapse rate.
Active Ingredients & Mechanism of Action
Active ingredient: Catechine aus Grüntee (Sinecatechine 10 %)
Active mechanism: The exact mechanism is not fully clarified. Catechins work over several ways:
- Antiproliferative: Inhibition of cell division in wart cells
- Antioxidant: Reduction of oxidative stress
- Antiviral: Inhibition of HPV replication
- Immunmodulating: stimulation of local immune response
- Pro-apoptotic: Promoting programmed cell death in infected cells
Clinical data:
- Clearance rate: approx. 54–65 % after 16 weeks
- Low fall rate: about 6–12 %
- Comparable with imiquimod at lower relapse rate
Who is it suitable for?
Veregen® is suitable for:
- Adults with outer genital and perianal warts
- Patients who prefer plant treatment
- Immune Competent Patients
Advantages:
- Vegetable active ingredient
- Very low drop rate
- Three times daily use (active treatment)
- Well tolerated
Not suitable:
- Internal warts
- Immunosuppressed patients
- Pregnancy and breastfeeding (inappropriate data)
Available Dosages
Dosing:
- Three times a day approx. Apply 0.5 cm long ointment string
- Apply to every single wart
- Maximum treatment time: 16 weeks
- Maximum application area: 250 mg ointment per application
Language:
- Average 10–16 weeks
- Continue treatment until warts are completely cured
- Apply no longer than 16 weeks
How to Take
Application: 1. Wash hands Two. Apply thin layer to each wart 3. Easy to rub 4. Don't wash ointment – let it act Five. Wash hands thoroughly
Important notes:
- Apply three times a day (morning, midday, evening)
- Not under occlusion
- Not on inner warts, mucous membranes or open wounds
- Avoid intimate contact directly after application
- Can weaken condoms and diaphragms
Contraindications
**Veregen® must not be used at:* *
- hypersensitivity to spinecatechins or other constituents
- Inside genital warts
- Open wounds
Preview at:
- Immunised patients (inappropriate data)
- Pregnancy and breastfeeding (no sufficient data situation)
- HIV-infected patients (restricted effectiveness possible)
Possible Side Effects
**Very common (> 10 %):* *
- Local redness (erythem)
- Itching
- Burn
- Pain / complaints at the job site
Family (1–10 %):
- Erosion, Ulzeration
- swelling, hardening
- Outflow (vaginal in women)
- Phimosis in men (same)
General: The local reactions are mild to moderate and sound after the end of the therapy. Systemic side effects are very rare.
Frequently Asked Questions
Similar Medications
Is Verification right for you?
A licensed doctor will review your information and issue a prescription if suitable. Discreet and secure.
Important Notice
This information does not replace medical advice. If you have questions about your health or the suitability of this medication, please consult a doctor. Read the package leaflet before use.